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Importantly, TNF type 1 receptor knockout mice are resistant to the initiation and progression of NAFLD in response to both high-carbohydrate and methionine- and choline-deficient diets 26,27

Other loop diuretics with better bioavailability and longer-lasting effects, such as bumetanide, torsemide, azosemide and piretanide, were introduced around this time as well (Murdoch and Auld, 1975

doi: 10.3171/2012.2.JNS111360

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